Thanks for asking me this question. Duodenal ulcer most commonly H.pylori infection may cause this problem. Excessive alcohol drinking may cause ulcer. More tobacco chewing and smoking is also risk factor. Some radiation therapy may lead to ulcer. Stressful condition may cause ulcer problem. If you don t treat the ulcer it may cause perforation also. Avoid spicy foods and alcohol drinking. Drink more water. Take care. Thanks.