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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What causes abnormal fetus growth by balanced translocation of chromosome?

Hi Doctor,
The would be mother is suffering from balanced translocation of chromosome which resulted abnormal fetus growth(high nucal transluency) for last two pregnancy.Means the fetus gets un-balanced translocation of chromosome.Is the donor's egg only way of getting a healthy baby?
Wed, 6 May 2015
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OBGYN, Maternal and Fetal Medicine 's  Response
Hi, I have gone through your question and understand your concerns. Presence of balanced translocation in parent has almost 50% chance of unbalanced translocation in the fetus. Fetus with unbalanced translocation abort or have abnormal growth or mental retardation.
Ineach pregnancy, fetal karyotype should be done to assess the chromosomal analysis.
Ovum donation rule out the possibility of this transmitted translocation in the fetus, hence you can go for it.
Hope you found the answer helpful.
Wishing you good health.
Dr Deepti Verma
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