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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Abnormal Diabetic Levels Despite Taking Medications?

My wife is on oral medication she is taking metformin twice a day 1000 gm, glymperide 4 mg before breakfast, and insulin glarizine in the night at 10 but then also the fasting glucose is above 300 in the morning, in evening it is between 200 to 220m pls advice. She is also taking medicine for hypertension ramipril 5 mf
Wed, 24 Aug 2016
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Pulmonologist,  's  Response
Thanks for your question on Healthcare Magic.
I can understand your concern.
Your wife is having uncontrolled type 2 diabetes.
Worsening insulin resistance is the likely cause for this.
In her drug list there still scope of two newer anti diabetic drug, pioglitazone and gliptans.
Start these new drugs after consultation with her doctor. Also increase the dose of her insulin.
Along with these, strict anti diabetic diet and exercise are needed.
Get done repeat sugar levels after 1 month of all these. If her sugar levels are still uncontrolled then she needs surgical help in the form of gastrectomy to reduce sugar absorption.
So consult her diabetes doctor and first discuss about starting newer drugs and increase dose of insulin.
Hope I have solved your query. I will be happy to help you further. Wishing good health to your wife. Thanks.
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What Causes Abnormal Diabetic Levels Despite Taking Medications?

Thanks for your question on Healthcare Magic. I can understand your concern. Your wife is having uncontrolled type 2 diabetes. Worsening insulin resistance is the likely cause for this. In her drug list there still scope of two newer anti diabetic drug, pioglitazone and gliptans. Start these new drugs after consultation with her doctor. Also increase the dose of her insulin. Along with these, strict anti diabetic diet and exercise are needed. Get done repeat sugar levels after 1 month of all these. If her sugar levels are still uncontrolled then she needs surgical help in the form of gastrectomy to reduce sugar absorption. So consult her diabetes doctor and first discuss about starting newer drugs and increase dose of insulin. Hope I have solved your query. I will be happy to help you further. Wishing good health to your wife. Thanks.