Hi, Thanks for posting in HCM. Soft lump at the wrist could be lipoma or ganglion. You need to get evaluated by a Surgeon for that. Lipoma can be removed by minor surgical procedure, to be done under aseptic conditions. Ganglion would best be aspirated as it arises out of joint. Surgical excision is recommended if the symptoms are not relieved by non-surgical methods. Hope the information provided would be useful. All the best.