Hi, Neither of these is either well studied nor FDA approved nor even a recognized therapy. First of all, the serum is cell-free liquid. It is not even slightly like a stem cell. Second, it is generally either stem cells from oneself (generally from fat). Or it is one s own blood serum. These are in development in the lab while they are already being used. Personally, I think this is unconscionable and would neither receive nor recommend their use. But there are many stories of success and the risk is scar tissue or infection and neither is common. But, if it isn t your material, your immune system will react to it and this will cause more scar, inflammation or other more serious effects. It just does not sound right. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Matt Wachsman, Addiction Medicine Specialist