Hi, Thanks for posting in HCM. I understand your concern. Prolia contains denosumab , which is a monoclonal antibody. Monoclonal antibodies are designed to target and destroy only certain cells in the body. It is used to treat osteoporosis in postmenopausal women who have high risk of bone fracture. The most common side effects of Prolia are back pain, pain in the arms and legs, high cholesterol, muscle pain, dermatitis, eczema, skin rash and bladder infection. Hope the information provided would be helpful. All the best.