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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Are The Side Effects Of Paracetamol Over Dose?

Hi, my friend took an overdose of paracetamol about 3 weeks ago. She was taken to hospital and treated for it. She was on a drip for 12 hours and at one point it was unsure whether she would live. She took 32 paracetamol and they were in her system for about 10 and a half hours. She has been told that she will be fine, but not to drink because of her liver but she says that since then she hasn't had her period. It has been long over due, and she's worried it has made her infertile. Is it possible that taking the overdose could have damaged her reproductive system? She is 16, about 5ft 4 and really slender. She has over dosed once before, at 13 but has had regular periods since then.
Mon, 17 Nov 2014
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Addiction Medicine Specialist 's  Response
ahhh... on a drip for 12 hrs.. very good.
Acetaminophen overdose kills the liver

Or... not. But the liver damage is over by now and will not get worse unless something else damages it (alcohol, other overdoses, viral infection of the liver). The acetaminophen toxicity is ACUTE, not lasting and the infusion if given fast enough, entirely prevents toxicity.
WOuldn't affect fertility. Shouldn't do that much to liver. Will not do anything more this long after the overdose.

ON THE OTHER HAND. Stress, anxiety, hospitalization often/usually affects periods. Temporarily.
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What Are The Side Effects Of Paracetamol Over Dose?

ahhh... on a drip for 12 hrs.. very good. Acetaminophen overdose kills the liver Or... not. But the liver damage is over by now and will not get worse unless something else damages it (alcohol, other overdoses, viral infection of the liver). The acetaminophen toxicity is ACUTE, not lasting and the infusion if given fast enough, entirely prevents toxicity. WOuldn t affect fertility. Shouldn t do that much to liver. Will not do anything more this long after the overdose. ON THE OTHER HAND. Stress, anxiety, hospitalization often/usually affects periods. Temporarily.