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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Are The Side Effects Of Letrozole?

What are chief side effects of estrogen suppressant letrozole 2.5 mgs daily? Used post breast cancer treatment for a woman in her 70s who is legally blind and recovering from breast cancer. Her husband has pulmonary fibrosis recently diagnosed. She also has had asthma and has arthritis. She lives in Connecticut. I am a friend just helping her discern side effects, some of them dermatological, which she cannot observe herself.
Tue, 25 Sep 2018
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General & Family Physician 's  Response
Hello,

Hot flashes, hair loss, joint/bone/muscle pain, tiredness, unusual sweating, nausea, diarrhoea, dizziness, and trouble sleeping may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.

Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including bone fractures, mental/mood changes (such as depression, anxiety), swelling of arms/legs, blurred vision, persistent nausea/vomiting, unusual tiredness, dark urine, yellowing eyes/skin.

This medication (and cancer) may rarely cause serious problems from blood clots (such as heart attack or stroke).

Get medical help right away if you experience: sudden shortness of breath, chest/jaw/left arm pain, confusion, coughing up blood, sudden dizziness/fainting, pain/swelling/warmth in the groin/calf, tingling/weakness/numbness in the arms/legs, slurred speech, weakness on one side of the body, vision changes, sudden/severe headache.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including rash, itching/swelling (especially of the face/tongue/throat/neck), severe dizziness, trouble breathing.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr Sanjay Kini, General & Family Physician
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What Are The Side Effects Of Letrozole?

Hello, Hot flashes, hair loss, joint/bone/muscle pain, tiredness, unusual sweating, nausea, diarrhoea, dizziness, and trouble sleeping may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including bone fractures, mental/mood changes (such as depression, anxiety), swelling of arms/legs, blurred vision, persistent nausea/vomiting, unusual tiredness, dark urine, yellowing eyes/skin. This medication (and cancer) may rarely cause serious problems from blood clots (such as heart attack or stroke). Get medical help right away if you experience: sudden shortness of breath, chest/jaw/left arm pain, confusion, coughing up blood, sudden dizziness/fainting, pain/swelling/warmth in the groin/calf, tingling/weakness/numbness in the arms/legs, slurred speech, weakness on one side of the body, vision changes, sudden/severe headache. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including rash, itching/swelling (especially of the face/tongue/throat/neck), severe dizziness, trouble breathing. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr Sanjay Kini, General & Family Physician