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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Are The Possibilities Of Bruga ECG Pattern Inheritance?

Hello, recently my brother has been told he has a type 3 Brugaa ECG pattern which needs additional investigation. As I am currently pregnant (with a boy), me myself and my family are very worried that the Brugada can be inherited in more than one member. My question is, as for example I have had about 100 ECGs in my entire life, is it possible for a Brugada carrier to not be identified until later on in life, or since this is genetic , ie present at birth, even childhood ECG can point to Brugada, or does it develop only later in life? This is also important as my brother wants to investigate old ECGs but I am not sure of their diagnostic values?
Mon, 30 Sep 2013
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Pain Medicine & Palliative Care Specialist,  's  Response
Hi,
Brugada is an inherited condition. However, the ECG may appear normal and therefore may not have diagnostic value. Some patients are given a drug (Flecanide) and the ECG examined under rest and exercise conditions. The ECG may then show the classical changes of Brugada syndrome.
It is possible for a carrier of Brugada to remain symptom-free and not show ECG changes and live a normal life. Old ECGs may not have diagnostic value as a normal ECG at rest do not rule out Brugada.
Hope this helps.
Regards,
Dr K A Pottinger,
MBChB FRCA
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What Are The Possibilities Of Bruga ECG Pattern Inheritance?

Hi, Brugada is an inherited condition. However, the ECG may appear normal and therefore may not have diagnostic value. Some patients are given a drug (Flecanide) and the ECG examined under rest and exercise conditions. The ECG may then show the classical changes of Brugada syndrome. It is possible for a carrier of Brugada to remain symptom-free and not show ECG changes and live a normal life. Old ECGs may not have diagnostic value as a normal ECG at rest do not rule out Brugada. Hope this helps. Regards, Dr K A Pottinger, MBChB FRCA