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Dr. Andrew Rynne

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Exp 50 years

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What are the effects of Nortriptyline on fetus?

I m 33 weeks pregnant and have been forced to change my medication (due to inability in the country) from 100mgs imipramine to 25mgs nortriptyline. (I am diagnosed with bipolar and am also taking 7mgs Seroquel). What are the expected effects on my baby? 2) could his change from imipramine to nortriptyline have something to do with my recently elevated blood pressure - now 142/89? thanks sandy
Tue, 22 Mar 2016
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Hello,
I have gone through your query and understood the concern. Nortryptiline has not been assigned any category by the FDA while it is a category C drug with AU TGA, which means the drug may cause harmful effects on the fetus without causing malformations. Neonatal withdrawal symptoms and anti-cholinergic symptoms may occur when used near term. Labile hypertension may also be associated with the use of this medication and regular monitoring is mandatory with its use. If you have switched over the medication yourself, please contact a specialist immediately for proper guidance. Hope this helps.
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