Hi , How are you doing ? From you history I can only say that you are having anovulatory cycles, may be PCOD/ some other hormonal problem. Clomid & Menopure are all hormones produced from your body itself. Hope you have , if nit try to find why this hormone imbalance ? With imbalance you will be risk for early abortions. Follicle of 10 mm & endometrium of 9mm is good but can t predict pregnancy. Let me give you a checklist to rule out possible causes Husband- Semen analysis at least 2- done 4 weeks apart preferably in an infertility center ( examination done by andrologist), Blood sugars Wife - Blood Sugars, Thyroid profile Ultrasound scans to evaluate Uterus , Ovaries & adnexa Confirm tubal patency- most important- Tube is the connection between uterus & ovaries( the bridge where sperm meets the egg & forms a baby) this is size of hair follicle & cannot be seen on scans. So check with HSG( Xray with dye), or SSG ( Scan with dye) or Laparoscopy From your history I presume you to have PCOD ( Polycystic ovaries), this is usually associated with Obesity, irregular cycles, no periods for few months & later heavy periods with clots & fleshy masses, Thyroid abnormality & prolactin problem indirectly. You develop that extra-pad of fat around the mid-segment of body, especially waist, thighs & breast, no fat beyond elbow & knees. Excessive body hair growth, hair fall , dark shade over lower half of face, acne , oily face skin, black skin over back of neck, inner thighs & under surface of breast. May have a family history of Diabetes, especially father or his family. Your expected weight should be Weight(in Kgs)= Height (in cms)-100 eg- If height 160cms, 160-100= 60-65 kg is expected weight. Once you reduce weight to normal range, you won t need any medicine to get periods or to get pregnant & pregnancy will be healthy. To reduce weight - NO FASTING, No junk food/ fast foods/ red meat, reduce snacks in between meals Have low calories food, high proteins Regular exercise, aerobics , yoga, brisk walking try to reduce 2-4 kgs / month. Don t hurry on weight reduction, it will be difficult to maintain. As soon as you reduce atleast 5 kgs , you will see changes. Even if you are in normal weight range , try this schedule, it will help. If all this done & found normal , nothing can stop a pregnancy with God s will Hope I have clarified your query All the best Dr.Balakrishnan