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Dr. Andrew Rynne
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What are my conception chances?

Hello Doc,
I was diagnosed with high FSH 12, last oct, now my fsh fluctuates between 4.9 to 6. I am getting treated with a Fertiliy clinic. I have gone through 2 IUI failed cycles. I am on third one now. Also my follicles grow erratically. With these do you think what are my conception chances?
Wed, 1 Feb 2017
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OBGYN 's  Response
Hi Devi,
I find your result erratic. FSH once raised ( More than 7 mIu/ml, bad if > 12miu/ml) cannot just come down like that, you have been mislead.
FSH is a hormone produced by a gland, Pituitary , in brain. FSH ( Follicle Stimulating Hormone) stimulates ovaries to produce eggs(which lies within follicles) . If eggs come in first say , FSH will not raise further, but if number of eggs in ovaries is reduced or not responding, especially around menopausal age, FSH will try to stimulate again , I mean higher dose of FSH come. It keeps increasing till eggs are released. So lesser the eggs , more the FSH will be. It will stay so. If your periods are regular with good flow forget about FSH or LH
FSH is always to be checked on DAY 3or 4 of periods. Even further confirmatory is Serum AMH in first half of the periods.
For IUI to be successful you will need good hormone stimulation from 2nd or 3rd day of cycle, till the day 10-13 of periods when follicles are right size to rupture.
As you have not given any other details like your age,other hormone levels, scan findings, husband factors etc.
Kindly see if the following checklist of investigations is done
Husband- Semen analysis at least 2- done 4 weeks apart preferably in an infertility center ( examination done by andrologist), Blood sugars
Wife - Blood Sugars, Thyroid profile
Ultrasound scans to evaluate Uterus , Ovaries & adnexa
Confirm tubal patency- most important- Tube is the connection
between uterus & ovaries( the bridge where sperm meets the egg &
forms a baby) this is size of hair follicle & cannot be seen on scans.
So check with HSG( Xray with dye), or SSG ( Scan with dye) or Laparoscopy
If all this done & found normal , nothing can stop a pregnancy with God's will
Hope I have cleared your query
All the best
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