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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What are all the receptors that marijuana affect?

What are all the receptors that marijuana affect? A lot of studies say it affects dopamine and serotin while others say it has nothing to do with those receptors and it plays in the CB1 and CB2 receptors but I want to know all the receptors that it imbalances in your brain so I can know if it can ( long-term ) imbalance chemicals that can induce psychosis , schizophrenia and other mental issues . I need an expert advice! and I want the truth not just what drugs do in general or government propaganda bs! Please help!!
Sat, 9 Feb 2013
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Psychiatrist 's  Response
Hi There, thanks for asking. It is an interesting topic. Cannabis has many (more than four hundred) active substances. Three of them are major ones and THC and Cannabidi and Cannabinol. They exert different effects because of the variety of the substances exist in it. Because they are derived from a natural plant, the properties varies from one plant to another. That makes its effect to be npredictable in each time which is consumed. Because most of the mechanism they act in hallucinogenic, they may cause permanent psychosis. Pure THC is used in medicine to control nausea or pain, but marijuana can affect many neurotransmitters like serotonin and dopamine as you mentioned secondary to nonspecific activation. So, its regular usage is strongly discouraged. I wish you the best enjoyment form life.
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What are all the receptors that marijuana affect?

Hi There, thanks for asking. It is an interesting topic. Cannabis has many (more than four hundred) active substances. Three of them are major ones and THC and Cannabidi and Cannabinol. They exert different effects because of the variety of the substances exist in it. Because they are derived from a natural plant, the properties varies from one plant to another. That makes its effect to be npredictable in each time which is consumed. Because most of the mechanism they act in hallucinogenic, they may cause permanent psychosis. Pure THC is used in medicine to control nausea or pain, but marijuana can affect many neurotransmitters like serotonin and dopamine as you mentioned secondary to nonspecific activation. So, its regular usage is strongly discouraged. I wish you the best enjoyment form life.