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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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VDRL Positive. Have Sore Throat. Is This Test Result Correct?

dear sir last week i did my medical test and i was VDRL positive after that ON doctors advice i underwent TPHA test which came negative??? i was asked by my doctor to take ampiclox for syphillis for which i am not convinced..... one more thing i had sore throat during this period of time ..can VDRL be psoitive due to bacterial throat infection?? if yes wht to do now???
Thu, 2 May 2013
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Infectious Diseases Specialist,  's  Response
Hello
Thanks for querry to HCM
As it is well known VDRL is a nontreponemal test designed for diagnosis of a sexually transmitted disease SYPHILIS.

VDRL is a very nonspecific test. TPHA is the specific test for syphilis. One of the major drawback of VDRL is that it gives false positive result in a battery of situations called Biological false positives.
VDRL is again of 2 types
1. Qualititive
2. Quantitative
Quantitative VDRL in most situations has the ability to exclude the biological false positives.

Get repeat testing done, if you are exposed to risk factor of a STD (you have not mentioned any exposure history).
Nothing to worry if it is a biological false positive.
All the best
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VDRL Positive. Have Sore Throat. Is This Test Result Correct?

Hello Thanks for querry to HCM As it is well known VDRL is a nontreponemal test designed for diagnosis of a sexually transmitted disease SYPHILIS. VDRL is a very nonspecific test. TPHA is the specific test for syphilis. One of the major drawback of VDRL is that it gives false positive result in a battery of situations called Biological false positives. VDRL is again of 2 types 1. Qualititive 2. Quantitative Quantitative VDRL in most situations has the ability to exclude the biological false positives. Get repeat testing done, if you are exposed to risk factor of a STD (you have not mentioned any exposure history). Nothing to worry if it is a biological false positive. All the best