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VDRL, TPHA patient, take treatment of penicillin injection. Still TPH positive. What to do ?

Halo doctor i am a pationed of vdrl and tpha -blood- serology r.p.r:- reactive 1: 4 dilution and Microbiology T.P.H.:-positive 1 in 320 dilution at present result (from one month i took treatment of penciline injection 6 times of every week in one with medicine also but the condition is in same percentge and positive. pleaase kindly give me the reason and what will do to get negaaaative.
Asked On : Wed, 20 Mar 2013
Answers:  1 Views:  546
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General & Family Physician 's  Response
Hi, thanks for using healthcare magic

Penicillin is considered and effective treatment for syphilis, alternatives are used if there is any allergy to the penicillins.
In general , after the use of the medication, repeat tests are done after 3 months, 6 months and 12 months.

If you only took the medication 1 month ago, it is possible that the titres or levels have not had the time to decrease.
You may want to wait the standard 3 months after treatment before checking your levels.

In general treatment is considered to have failed if :(1) signs and symptoms reoccur (2) there is a 4 fold or times increase in levels of the vdrl (3) there is no 4 fold or times decrease in levels within a year

I hope this helps
Answered: Sat, 27 Jul 2013
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