Hello. I m sorry you re having difficulties conceiving. Your two missed periods in September and October, along with multiple negative pregnancy tests, indicate that you haven t been ovulating normally. When you don t ovulate, the lining of your uterus continues to thicken under the influence of estrogen, which is a hormone your body normally makes during each menstrual cycle. If this isn t addressed, it can lead to problems. Your doctor prescribed Sysron to withdraw your uterus from the estrogen, and it sounds like the medication worked as it should have. The pain you feel in your lower abdomen could be an indication of a problem that is interfering with your monthly cycles, such as an ovarian cyst or endometriosis. These issues will need to be addressed by your physician, and I suggest you return to him or her to discuss the next step in your evaluation. I hope things settle down soon!