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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Took Eptoin For Seizure Resulting In Steven Johnson Reaction. Did Not Respond To CBZ. Suggested Valance Or Encorate Chrono. Will This Worsen The Situation?

I had a seizure and was administered with Eptoin ( Phenytoin ) which caused Steven Johnson reaction. Then I was administered with CBZ and that did not suit me as well. Now I have been suggested Valance OD or Encorate Chrono by my Gen Phy and I am hoping that this will not worsen the situation. My neuro had also started Levipil but that caused drowsiness and attention problems.
Thu, 14 Feb 2013
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Neurologist 's  Response
Hi Ravi,

Thank you for posting your query.

It is unfortunate that you developed severe allergic reactions to phenytoin.

You should also avoid the following medications- carbamazepine, oxcarbazepine, phenobarbitone, as they can also cause allergic reactions.

I agree that encorate chrono is the most suitable anti epileptic drug for you.

Best wishes,
Dr Sudhir Kumar MD DM (Neurology)
Senior Consultant Neurologist
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Took Eptoin For Seizure Resulting In Steven Johnson Reaction. Did Not Respond To CBZ. Suggested Valance Or Encorate Chrono. Will This Worsen The Situation?

Hi Ravi, Thank you for posting your query. It is unfortunate that you developed severe allergic reactions to phenytoin. You should also avoid the following medications- carbamazepine, oxcarbazepine, phenobarbitone, as they can also cause allergic reactions. I agree that encorate chrono is the most suitable anti epileptic drug for you. Best wishes, Dr Sudhir Kumar MD DM (Neurology) Senior Consultant Neurologist