I have Graves disease and had my thyroid removed by Nuclear Medicine 2 years ago. The medical team decided to wait 6 months before putting me on Thyroxin. In that time I gained an incredible 25 kilos. It has been extremely difficult to lose the weight, although I lead an active healthy lifestyle. Short of starving myself, is the only way. I know this as this year I resorted to an intragastric balloom and lost 23 kilos. It was not a healthy way to lose the weight as I was literally starving by the end of the 5th month and had to have it taken out before the 6mth time frame. It has been 5 mths since and I am slowly regaining the weight, up to 7 kilos now. I exercise 2 hours daily by, running and walking, resistance training and vibratraining. I used to own a gym and now what is required. I am considering Duromine and wonder is this is possible while being on 100mg of Thyroxin. The only reason I am considering this is that you begin to feel like a failure, yet you are trying everything. To do what I did re the balloon was extreme for me, however I could not see a light at the end of the tunnel. I am thinking if I could just suppress the appetite enough to maintain my current weight, I would be both mentally and physically healthier. I am 47, weight 79kgs, height 5ft 7. Have averaged between 64 and 69kilos since all of my children have been born, until being diagnosed, where my weight was up too 95kilos! Please advise....