Thanks for your query. Prestiq is venlafaxine
which is classified under SNRI group of drugs whereas Zoloft is sertraline
which is classified under SSRI group of drugs. Both the drugs are equally efficacious anti-anxiety as well as antidepressant agents.
If there is complete non-response to one drug even after a month, it is worth considering a different class of anxiolytic agent. The other treatment options include psychotherapy
techniques like cognitive behavioural therapy.
I would also suggest yoga, meditation
and breathing relaxation exercises to supplement your treatment. I would also advise thyroid function tests
to rule out thyroid disorders presenting as anxiety symptoms.
Hope you found the information useful.