Thanks for posting your query.
and related drugs are immunosuppressants and may give opportunistic infections a chance to cause problems. mouth and gut ulcers also a frequent problem. Anemia
is also found commonly.
The side effects can be controlled to large extent if you take folinic acid tablets if you are not taking one.
There are other drugs which may be tolerated by you eg.- Leflunomide
You can switch to them in consult with your local clinician.
I hope this answers your query.
In case you have any follow up queries or doubts, you can forward them for me, and I shall be glad to help you.
Please accept my answer in case you do not have further queries.
Wishing you good health.