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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Taking Methotrexate For RA. Suffering From Side Effects. Fuzzy Head, Sleeplessness, Stomach Upset. Can I Taper The Medication? On Prednisone

I m on methotrexate 15mg for RA, I would like to give it up because the side effeects are a bother? Fuzzy head, can t sleep, upset stomach . If I was to stop cold turkey would I react to sudden stop, or could I start to decrease gradually? Also on predisolone but down to 3mg daily and frolic acid 5mg x 2 per week. Thanks Barry
Sat, 21 Jul 2012
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  User's Response
hi,
Since you have developed side effects to oral methotrexate you can consult your physician for injectable methotrexate with oral folicacid.If u have persistent side effects u can switch on to oral Cyclosporin after renal function test and regular BP monitoring.
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Taking Methotrexate For RA. Suffering From Side Effects. Fuzzy Head, Sleeplessness, Stomach Upset. Can I Taper The Medication? On Prednisone

hi, Since you have developed side effects to oral methotrexate you can consult your physician for injectable methotrexate with oral folicacid.If u have persistent side effects u can switch on to oral Cyclosporin after renal function test and regular BP monitoring.