Hi, tonight it is one of my best friend's 18th birthday, so obviously there is going to be a drinking party. Now I have been on Macrobid antibiotics for the past 2 days due to a UTI. I was wondering if there was any way I could drink tonight? I know that alcohol makes the frequency to urinate greater, but I am no longer in pain so would this be an issue? Also, would the antibiotics be effected by the alcohol? I read somewhere that if you drink a while after the medication has been taken that there will be no effect and that the medication will remain unharmed as it has already been absorbed in the system.