Hello! Thanks for posting your query. Metformin (bigomet) is used to treat type 2 diabetes. It has also been found to help with PCOS symptoms.In about 25% of women metformin causes side effects which may include abdominal discomfort, cramping, diarrhea and nausea. The side effects may be severe enough to make the woman stop the metformin medication. Metformin is taken in a dose that the woman can tolerate. Most people can tolerate 500 mg three times daily, if they build up to that dose gradually. Metformin is started at 500 mg once daily, increase to 500 mg twice a day after one week, then to 500 mg 3 times daily after another week.If the 3 times daily dose cannot be tolerated due to side effects, we remain on the twice-daily dose. The most effective dose of metformin for PCOS is generally 500mg 3 times daily. If the metformin does not result in ovulation and regular periods, the next step is often adding clomiphene to the metformin. If the combination of metformin and clomiphene does not result in ovulation then we move on to other options of injectable FSH,Latrezol etc. Metformin is essential and needs to be continued for long term as there are chances of developing diabetes and metabolic syndrome in later life which will be more cumbersome.Also to regain normal fertility it is essential to continue metformin. You can consult with Gynacologist and endocrinologist for treatment options. Hope this will help you.