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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Taken Mext, Sazo, Defza. Have Liver Dysfunction. Worry Much?

hi doctor, i have liver dysfunction after taking mext. now doctor stopped mext but prescibed sazo, defza and hcqs.Can i take these drugs with such liver dysfunction?(sgpt 55, sopt 44, bilirubin1.1). is theer any alternatve of methotroxate which do not affect liver? very much worried abt my liver.. but cant stop medicine due to severe joint pain if i stop so..
e mail: YYYY@YYYY
Thu, 13 Jun 2013
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General Surgeon 's  Response
Hi and welcome to HCM. Thank you for your query.
There are no alternatives unfortunately. These are medicines with bad effect on liver and you just need to do frequent liver LFT sheck ups and ultrasounds. YOur doctor must determine cost-benefit of these cytotoxic medicines. Also, this isnt significant elevation of LFT and it diosnt mean that liver function is compromised very much. Wish you good health.
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Taken Mext, Sazo, Defza. Have Liver Dysfunction. Worry Much?

Hi and welcome to HCM. Thank you for your query. There are no alternatives unfortunately. These are medicines with bad effect on liver and you just need to do frequent liver LFT sheck ups and ultrasounds. YOur doctor must determine cost-benefit of these cytotoxic medicines. Also, this isnt significant elevation of LFT and it diosnt mean that liver function is compromised very much. Wish you good health.