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Taken Forecox for tuberculosis. Have skin discoloration. Due to rifamcin?

hi Dr this is dhamo from mumbai sir I was diagnosed with tuberculosis before six months. I have a matted lymponade on right side of my neck and undergone a treatment of forecox tablet for first four months...aftr four months know im taking the tablet of RHE FD and benadon tablets Know issue is that I can realize discolouration of my skin tone... which is becoming this happens due to heavy tablets of rifamcin Can recovereded my skin tone bcoz being an indian it is important sir plz sort my problem sir as I
Asked On : Fri, 23 Nov 2012
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Pathologist and Microbiologist 's  Response
Hello and welcome to HCM
Forecox is a combination of rifampicin, isoniazid, etambutol and pyrazinamide. RHE FD and benadon are also the same drugs with different propeitary names.
They are first line drugs for tuberculosis.
None of these drugs cause discoloration/ hyperpigmentation of skin.
Infact there are couple of other side effects which should be promptly reported to your treating doctor.
These side effects are tingling sensation, joint pains, vision problems etc.
Other side effects which are not veru serious are fever, rash, flu like symptoms, abdominal discomfort, nausea, diarrhoes, orange discoloration of urine, tears etc to name a few.
There is some other cause for discoloration. Some of causes for skin discoloration/ hyperpigmentation eg pregnancy, sun exposure, endocrine disease like Addison disease, post-inflammatory hyperpigmentation.
Consult you dermatologist for clinical examination, investigations and management.

Thanks and take care
Dr Shailja P Wahal
Answered: Sat, 24 Nov 2012
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