Hi and welcome to HCM. Stop the dam stuff. Keto aminoacids have not been proven to be of any benefit at all, but still widely prescribed in India (no where else in the world can people be fooled like here!!). At the very least it should not cause any harm. However if the Creatinine has jumped up so quickly, something is wrong here, and it might/ might not be the new medicines that you started. Many medicines can cause a kind of inflammation in kidneys called Interstitial Nephritis which can cause sudden deterioration in kidney function (especially in those with sub-optimal kidney function). The cause of deterioration might be something totally different - hence very important to get back to your )or another) nephrologist and get yourself checked out. Bur stop the new medications straight away. Best wishes