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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Treatment To Manage Chronic Allograft Nephropathy

reanal transplant done 0n 22-2-2010.medicne going on as follows

tacrolimus 1.5mg twice

azaron 50 mg once

wyslon 5 mg



after one year serum creatnine is coming 1.5. biopsy test carried out result as follows

chronic allograft nephropathy.

medicene changes

everolimus 0.5 mg given instead of tacrolimus

suggest what to do & any other treatment
Mon, 7 Aug 2017
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Nephrologist 's  Response
Dear Patient,

in general we decide treatment after an accurate review of the renal biopsy. Was rejection extensive? how much severe? Chronic allograft rejection is a general diagnosis since it does not allow to distinguish a predominant antibody or t cell mediated process. By the way, I assume the therapy that you took before the renal biopsy was not appropriate to stop rejection. Please report the levels of the drugs are you currently taking. Moreover, report the levels before the renal biopsy and the biopsy report. Then, we will help you to find out if everything is ok. Remember also that if you have high levels of antibodies against donor and 7 years of transplant, you may see some chronic changes.
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Suggest Treatment To Manage Chronic Allograft Nephropathy

Dear Patient, in general we decide treatment after an accurate review of the renal biopsy. Was rejection extensive? how much severe? Chronic allograft rejection is a general diagnosis since it does not allow to distinguish a predominant antibody or t cell mediated process. By the way, I assume the therapy that you took before the renal biopsy was not appropriate to stop rejection. Please report the levels of the drugs are you currently taking. Moreover, report the levels before the renal biopsy and the biopsy report. Then, we will help you to find out if everything is ok. Remember also that if you have high levels of antibodies against donor and 7 years of transplant, you may see some chronic changes.