Hello! I have been through your question. Valley Fever (Coccidioidomycosis) usually causes a primary pulmonary infection (as I think you have based on your history) which often resolves without therapy.  In some cases a chronic  pulmonary infection or, rarely, disseminated disease (extrapulmonary infection) may develop. Primary pulmonary cocci usually may not need treatment but it depends from risk factors , illness severity indicators, and findings on follow-up of patient’s symptoms, exam, and serology every two to four weeks. Usually it treats with fluconazole 400 mg daily or itraconazole 200 mg twice daily until titer is stabilized at ≤ 1:4 and asymptomatic. The infection could be clear when the titer is usually 1:2, 1:4 or undetectable. Persistence of titer 1:4 as you have (1-16) may indicate active infection including dissemination, but to be sure I want to ask this titer result is after starting the treatment or in the beginning. I think is a good news that your symptoms are improved but you need to do a physical examination by an Infectious disease specialist,every two weeks titer, lab test and chest radiography as well to define better your situation. I hope my answer help you. I wish you a quick recovery.