Dear Friend Welcome to Health care magic. I am Dr Charu , I will shortly try to help you with my opinion. i am very sorry to say but there is no permanent cure of psoriasis till date. Various good medications are available for treatment like oral methotrexate, cyclosporin which are started in case of large body area involvement after ruling out any contraindications for use. Medications are advised as per need of patient when required. Based on the available details, this is my best advice for you. You should discuss with your doctor and share my opinion , I am sure he/she will agree to my opinion. Good Luck.