Thanks for your question on HCM.
I can understand your situation and problem.
Your sister is having stage 4 pancreatic cancer.
Stage 4 means it is inoperable and incurable as well.
The only treatment option is
chemotherapy.
Radiotherapy is not indicated in pancreatic cancer.
So we are left with chemotherapy only.
And chemotherapy drugs have their own side effects and can not tolerate by all patients.
So we need to check it's response after 2-3 cycles.
Your doctor is doing the right thing.
So stick to his treatment.
Better to discuss end of life issues,
palliative care and nutritional things with your sister.