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In this case one option is remaining i,e allogeneic stem cell
transplantation — stem cell transplantation from a suitable donor — is the only treatment that has the potential to cure
myelofibrosis. But it also has a high risk of life-threatening side effects.
Many people with myelofibrosis, because of age, stability of the disease or other health problems, don't qualify for this treatment.
Prior to a stem cell transplant, also called a
bone marrow transplant, you receive very high doses of chemotherapy or radiation therapy to destroy your diseased bone marrow. Then you receive infusions of stem cells from a compatible donor.
After the procedure, there's a risk that the new stem cells will react against your body's healthy tissues, causing potentially fatal damage (
graft-versus-host disease). Other risks include organ or blood vessel damage, cataracts, and the development of a different cancer later on.
so
palliative care is done for on going symptoms.
Take care
Regards,
Dr. Akhilesh Kumar, Physical Therapist or Physiotherapist