Thanks for your question on Healthcare Magic. I can understand your concern. Multiple matted arrhythmia with pruritus can be due to urticaria (skin allergy). And in my opinion, it is better to give combination of anti allergic (montelukast) and anti histamine (fexofenadine) instead of plain fexofenadine. You can also apply steroid cream (mometasone). In severe cases, oral steroids (prednisone) is also advisable. If he still feels itching then consult dermatologist and get done clinical examination and skin Biopsy for confirmation. Hope I have solved your query. I will be happy to help you further. Wishing good health to your brother. Thanks.