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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Treatment For Metastatic Adenocarcinoma In Lungs

Please let me know if Hyperthermia(whole body/local) treatment with combination of Radio & Chemotherapy [Thermo-Radio-Chemo combination ] is applicable & effective at nanavati center.

Dear Sir
Please let me know if I am eligible for Hyperthermia(whole body/local) treatment with combination of Radio & Chemotherapy [Thermo-Radio-Chemo combination to overcome the cancer resistance against chemo alone or radio alone ]
Current Complaints

Metastatic adenocarcinoma in lung. Adenocarcinoma spread in both lung.
History : treated for endometrum cancer at Kidwai Memorial Institute Of Oncology Bangalore in Dec 2010. Surgery followed by radiotherapy was done for endometrium. Hot spot in lung in Dec 2010 PET scan was considered as Granuloma due to no uptakes shown in PET scan. Now CT scan & biopsy (through EBUS) technique confirmed that it's adenocarcinoma type of tissues. Origin has been confirmed: It's endometrium (Uterus). We met pulmonologist Dr Ravindra M Mehta (Appolo, Bangalore) and he suggested Stenting to ease the breating as there is 90% blockage of right lung airways. Oncologist at Kidwai Memorial Institute of Oncology , Bangalore have been suggested Chemeotherepy as next step. But before that they decided for stenting to cure 90% blockage (due to tumor) to improve the patient condition.
Stenting is done [Right Bronchus].

brief clinical history- history of endometrial adenocarcinoma.
specimen-EBUS- Transbronchial needle aspiration of mediastinal lymphnode

Gross Examjnation- received 10 H and E stained slides.
2 slides- Station 4R, 2 slides- Station 11L, 2 slides- Station 4L, 4 slides- Station 7

cytological features are suggestive of metastatic adenocarcinoma- Station 4R, 11L, 4L AND 7

Treatment for recurrent cancer (no reoccurrence at surgical site but spread in bilateral lung):

Has gone through 10 cycles of chemo (weekly) with below regimen (at Mzumder shaw cancer center under supervision of Dr Vineeta Binoy & Dr Bharat):

Carbo platin (kemocarb) : 130 mg
Abraxane (nano particle drug delivery for paclitexal): 200mg
Neopojen (Growth colony factor- GSF-300 mcg for two continuous day after every round of chemo)

Before the above regimen, she had gone through one round of below chemo:

Cisplatin
Adriamycine
Docitexal
GCF

As she could not tolerate the very first regimen (Cis platin based), she was put on 9 cycles of second regimen (as described above).

Results:

Plural effusion gone
Good response as tumor shrank (largest lession before chemo was 3.2 cm, now after chemo it's reduced to 1.5 cm).
Medistinal lymphnodes also reduced in size.

Please refer the latest PET scan report

Please let me know if I am eligible for Hyperthermia(whole body/local) treatment with combination of Radio & Chemotherapy [Thermo-Radio-Chemo combination to overcome the cancer resistance against chemo alone or radio alone ]
Thanks,
Premavati Shukla
52 Y (Female)
Tue, 27 Nov 2018
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Oncologist 's  Response
Hello,

There is a lot of treatment for lungs cancer witch its dependent from the stage of the diseases. Immune therapy has very success in the treatment of the disease.

Hope I have answered your query. Let me know if I can assist you further.

Regards,
Dr. Esmeralda Sera,
Oncologist
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Suggest Treatment For Metastatic Adenocarcinoma In Lungs

Hello, There is a lot of treatment for lungs cancer witch its dependent from the stage of the diseases. Immune therapy has very success in the treatment of the disease. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Esmeralda Sera, Oncologist