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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Treatment For Mesenteric Panniculitis

Hi there. I live in the UK and have been diagnosed with Mesenteric Panniculitis. Neither my GP or Surgeon know much about it at all. I am awaiting a CT in January. I was diagnosed via MRI. I look like I am giving birth to quads ( I was a UK size 14) I am 47 and I feel general unwell/ not with it. Have been signed off sick for the last two weeks from work. ( I am a community School staff nurse) . My GP has stated me on Prednisolone 40mgs. How can I help myself? Can I follow a special diet? I feel really uncomfortable. Any advice would be gra telly appreciated. Many thanks.
Fri, 30 Sep 2016
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Neurologist, Surgical 's  Response
Hi, ,thanks for query.You are having a rare disease.
For mesenteric panniculitis ,corticosteroids are the initial treatment
of choice.
Additional anti-inflammatory drugs that have been used to treat mesenteric panniculitis include colchicine, azathioprine, cyclophosphamide, infliximab and pentoxifylline.
A prospective clinical trial has demonstrated that the drug thalidomide improves symptoms .
Low dose naltrexone (LDN) is also a promising new therapy for mesenteric panniculitis.
Tamoxifen and other hormonal therapies have been proposed to treat patients with mesenteric fibrosis .
Thanks
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Suggest Treatment For Mesenteric Panniculitis

Hi, ,thanks for query.You are having a rare disease. For mesenteric panniculitis ,corticosteroids are the initial treatment of choice. Additional anti-inflammatory drugs that have been used to treat mesenteric panniculitis include colchicine, azathioprine, cyclophosphamide, infliximab and pentoxifylline. A prospective clinical trial has demonstrated that the drug thalidomide improves symptoms . Low dose naltrexone (LDN) is also a promising new therapy for mesenteric panniculitis. Tamoxifen and other hormonal therapies have been proposed to treat patients with mesenteric fibrosis . Thanks