I am a 70 year old female. Several years ago, I had an appointment with a DR. COWLS (not sure of spelling). I was diagnosed with hyperthyroid and was told that the blood test result was 92. I am still on the synthroid. I lost a total of seventy pounds and felt like a new person. The synthroid has been adjusted adjusted several times over the past years. Several months ago, I , again gained weight, depressed, hot flashes, sore muscles and memory is not as sharp as it was. I had an appointment, in June, with a different doctor. This was recommended by my gynecologist. After many blood tests, scans of my arm muscles, etc. I was told that my Vitamin D was VERY LOW. For approximately 3 months, I took 50,000 units of this vitamin and again lost some weight, hot flashes gone, memory was clearer, no hot flashes, etc. After more blood tests, I received a call from a call from a nurse stating that my levels were still quite low and they increased the Vitamin D2 1.25MG to twice a week. I began this dosage about 3-4 weeks ago. My symptons have returned. Hot flashes, weight loss has slowed down, EXHAUSTED. I was doing better on the 50,000 units than I am on the 100,000 units. I was informed by the nurse that my blood test are still quite low. I am taking synthroid, 150 MCG tablet, once every day. I have been told that my thyroid levels look fine. I do not understand what is going on. I HOPE YOU CAN HELP ME WITH THIS PROBLEM. Sincerely, Karen