Hi, I have gone through your query and noted the onset of new symptom of pain in your right shoulder. It is not related to the L5-S1 herniated disc as the nerves that are being impinged by the protruded disc do not supply the area in the shoulder. However I also noted that your pain and numbness symptoms haven t gone away inspite of the second injection. I would suggest you to see your Spine surgeon or orthopedist and follow up with him for further management of your symptoms. Hope this has answered your query.