Hi As the pancreas is an integral part of the digestive system, it would stand to reason that gastrointestinal symptoms would figure prominently in pancreatic cancer. Nausea and vomiting may be a problem in up to 40% of pancreatic cancer patients. The cause of these symptoms are varied-and can range from, for example, a reaction to chemotherapy or radiotherapy – to being a sign of mechanical obstruction of the small bowel. Consequently, the reason for the nausea and vomiting (sometimes referred to as “emesis”) needs to be sought out–and the underlying cause dealt with appropriately In addition, anti-emetic agents may be prescribed Indigestion, diarrhea and a change in bowel habits are not uncommon in pancreatic cancer. The causes can range from the more mundane to the serious – and may, for example, include laxative overuse, malabsorption, anxiety or stress, infection, medication side-effect, radiation therapy, the effect of the cancer itself, surgery, pancreatic enzyme deficiency — and can even represent a sign of bowel obstruction. The treatment is individual, but should include evaluating and correcting any underlying problems. Food and fluid regulation are likely required. And anti-diarrheal medication may be indicated Wish you mom good health Regards Dr Sridhar K