I have auto immune disease and thyroid is non-existent. I have on occasion had my entire left ear inside and out, lobe cartilage and glands in my face on that side as well as my head,neck and arm pit swell up very large. the ear is purple in color and I am in a lot of pain. Seems like this flare-up which is so painful, happens during stressful times in my life. 1990 it got so bad I was hospitalized for 5 days with IV abx..I am dealing with this issue at this time..