Hello, Doctor. I found this Web site on a search engine link after typing in the keywords, Saline IV causes stomach bloating? . My name is Nicole. I was 27 in January 2014 when I experienced very tight chest pain & the sensation of feeling like I couldn t breathe when I finished my plasma donation at a new Plasma Donor center. The last part of the donation calls for saline to run through the IV so it can calm the heart rate & sort the blood back to normal preventing clots. I alerted the employees at the facility that my chest was very tight. That employee had a nurse come in to check me. Later, paramedics made two trips to see me. I had told them to leave since I was feeling better. After several minutes of monitoring, sitting up in the waiting room eating gold fish & sipping on water, my heart rate never got below 120. When paramedics arrived the second time & placed me on the gurney, heart rate was at 150. I told one of the paramedics my heart was never this high when at rest or sitting down. After being hooked up to an IV at the ER, my heart rate never got below 99. That didn t shock me too much. I went in the plasma place feeling anxious due to the frigid temperatures outside & having a lot of anxiety-induced thoughts in my mind. However, I felt fine until the saline went thorugh my system at the end of the donation process. Keep in mind this was only my second donation. My first donation was a success with no issues a couple of weeks prior. Do you think the saline solution might have caused my chest to become tight due to bloating my stomach?