Hello my name is Shirley .Ihave been using estrace for dryness. I am a diabetic and over weight and my breast have been breaking out for sometime. I use clotrimazole and betamethasone cream and they clear up. I have started breaking out on the outside of my vagina and legs so i presumed it was heat but the cream does not clear it up. its getting worse and looks like it my be going to have blisters on it .could it be from the Estrace cream, or is it just heat.