Hello Mr Bhaskar, Welcome to HCM.. Thank you for posting your query.. I read your question completely and have understood it well.. And I am really sorry for two things. 1. The health status of your uncle 2. About the Urologist who offered a surgery. See, we come across so many such cases of prostate enlargement. Largely called as BPH. But it is never ever such urgent that in a span of 3 days from angioplasty, the surgery had to be done. And, regarding stopping of tablet like Ecospirin, I am totally against it. Because, life is more important than prostate. As simple as that. And definitely,there will be chances of MI, heart attack once he stops those medications. Generally, forget about 3 days gap, even after few years, we surgeons take opinion from cardiologist or at least a physician on stopping of such drug and then, go operate. That is called fitness for surgery. But I was shocked to hear from you that, a urologist asked you to stop such life saving drugs. Feel bad as a doctor myself. And I feel no doctor will do that as far as I know. Hope this helps you Take care and God bless.