Stomach cramps are extremely painful but it s possible to relieve them using home remedies that are easy and effective. There are many possible causes of stomach cramps and they can affect or emanate from your digestive organs, your aorta, your appendix, your kidneys, or your spleen, or they can originate from an infection elsewhere in your body. 1. Cramps are commonplace for some women during their menstrual cycle, although exercises can often alleviate such pain. The strength of pain does not necessarily indicate seriousness: very painful cramps can be caused by gas passing through your digestive system harmlessly, whereas life-threatening conditions such as colon cancer and early appendicitis can produce mild or even no pain, 2. so care needs to be taken not to judge the cramp severity according to your pain level.