Respected user , hi I evaluated your query thoroughly. @ All your problems are inside your current medications !! * Lodrain has side effects as difficulty in breathing, tightness in the chest , shortness of breath. * Vyvance has insomnia as a side effect . You need detail counselling with her Consultant , discuss about these mentioned issues & she definitely requires dose alterations or changing of the molecule keeping her in this condition. Hope this helps you . Thanks for using Health care magic & giving me an opportunity to assist you. Wishing her a very happy healthy life ahead devoid of chest pain. Welcome for any further queries. Regards dear take care.