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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Remedies For Elevated ALT And AST Levels With Poor Liver Function

I m 37 yoa male and have been a heavy drinker for some time now. I just had my blood work done and the results came back saying my ALT and AST are both and the 200 s and my liver function is poor. I quit drinking and was wondering how long will it take to have everything back to normal levels? I do have to go back for follow up blood work next week and take a ultrasound. When the nurse called with my results he didn t give much insight on what was going on and whether I was dying or what was going on. Kinda concerned
Mon, 22 Jul 2019
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General & Family Physician 's  Response
Hello,

Patient with an alcohol intake of 30 or more grams per day (one standard drink contain 14 grams of alcohol) are at increased risk of cirrhosis, although the majority of patients will not develop cirrhosis despite heavy alcohol intake. Alcohol abuse may lead to steatosis, steatohepatitis, cirrhosis, and hepatocellular carcinoma. Not all patients who drink heavily develop alcoholic liver disease. However, once alcoholic liver disease develops, continued alcohol use typically leads to persistent and often progressive liver disease. Hepatic inflammation (hepatitis) in patients with alcoholic liver disease increases the risk progressing to cirrhosis and mortality. Several additional histologic features have been described that are associated with a worse prognosis, including the presence of perivenular fibrosis and a mixed pattern of macrovesicular and microvesicular fat.

Your doctor will see you abdominal ultrasound to see if you any cirrhosis. General approach management of alcoholic liver disease centers on alcohol abstinence. In patients who have not yet progressed to cirrhosis, abstinence may allow for reversal of the hepatic changed induced by alcohol. If you have cirrhosis, alcohol abstinence decreases the risk of hepatic decompensation and improves survival. Patients should be referred for treatment for alcohol abuse or dependence to increase the likelihood of successful abstinence.

Patient with decompensated cirrhosis are managed the same as patients with other form of end-stage liver disease and require treatment for complications such as ascites, variceal bleeding, and hepatic encephalopathy. In some cases, liver transplantation may be required.

Talk to your doctor to have a good plan for you.

Hope I have answered your query. Let me know if I can assist you further.

Regards,
Dr. Heang Chan Raksmey, General and Family Physician



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Suggest Remedies For Elevated ALT And AST Levels With Poor Liver Function

Hello, Patient with an alcohol intake of 30 or more grams per day (one standard drink contain 14 grams of alcohol) are at increased risk of cirrhosis, although the majority of patients will not develop cirrhosis despite heavy alcohol intake. Alcohol abuse may lead to steatosis, steatohepatitis, cirrhosis, and hepatocellular carcinoma. Not all patients who drink heavily develop alcoholic liver disease. However, once alcoholic liver disease develops, continued alcohol use typically leads to persistent and often progressive liver disease. Hepatic inflammation (hepatitis) in patients with alcoholic liver disease increases the risk progressing to cirrhosis and mortality. Several additional histologic features have been described that are associated with a worse prognosis, including the presence of perivenular fibrosis and a mixed pattern of macrovesicular and microvesicular fat. Your doctor will see you abdominal ultrasound to see if you any cirrhosis. General approach management of alcoholic liver disease centers on alcohol abstinence. In patients who have not yet progressed to cirrhosis, abstinence may allow for reversal of the hepatic changed induced by alcohol. If you have cirrhosis, alcohol abstinence decreases the risk of hepatic decompensation and improves survival. Patients should be referred for treatment for alcohol abuse or dependence to increase the likelihood of successful abstinence. Patient with decompensated cirrhosis are managed the same as patients with other form of end-stage liver disease and require treatment for complications such as ascites, variceal bleeding, and hepatic encephalopathy. In some cases, liver transplantation may be required. Talk to your doctor to have a good plan for you. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Heang Chan Raksmey, General and Family Physician