hello there and thanks for writing to HCM I read your query and will surely help you out following details would have really helped: your age and sex? whether you have any other medical or surgical or drug history? what side effects did you experience with reclast and boniva? coming to your query, i would suggest you use bisphosphonates itself first. Since you have experienced a bad response to two bisphosphonates that is reclast(zoledronate) and boniva(ibandronate),i would recommend you to take alendronate or risedronate (other bisphosphonates)orally Try to take the tablet on empty stomach with a glass of water and wait for half an hour before having lying or having food. this might help in relieving side effects stomach upset and heartburn a bit If you are still intolerant to above drugs,i would recommend to ask your doctor for injections like teriparatide and/or denozumab with less side effects. If you are a woman past her menopause,i would recommend taking hormonal preparation like raloxifene i would also recommend you have a diet rich in calcium and vitamin-D and then take supplements if needed.Also do light exercises.And also quit smoking and alcohol Though you cant completely reverse osteoporosis,all this will help you. Hope i have clarified your query and hope it helps. Followup if you have doubts. Take care and Good day