Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Chronic urticaria can be treated with long term antihistamines such as Levocetrizine and Fexofenadine. In case of lack of response to antihistamines, you can use cyclosporine, autologous serum injection etc. But, do take care of underlying thyroid disease as thyroid disease is one of the causes of chronic urticaria. If hives occur even after normalizing thyroid function, you can go for drugs such as cyclosporine. Hope I have answered your query. Let me know if I can assist you further.