Hi.. Welcome to HEALTHCARE MAGIC.. I have gone through your query and can understand your concerns.. As per your complain Pilonidal sinus is a small cyst or an abscess that occurs at the top of the buttcrack and at the lower end of tailbone.. In active and infected stage it is highly painful and can interfere with sitting and moving.. It can occur due to a number of causes like: -Traumatic injury to the lower portion of tailbone or top of buttcrack. -It can occur due to ingrown hairs. -Long sitting hours. -Low Immunity. -Rubbing with clothes.. As you have already been treated with homeopathy and allopathic with no definitive relief, , the last resort left is surgical drainage.. You can however be given antibiotics and anti inflammatory painkillers to reduce infection and heal the sinus.. But in case if it still does not resolve then surgical drainage of the lesion followed by complete removal of pus, ingrown hair [if present ] and thorough debridement of the wound and doing antiseptic dressing will be done.. Regular change of dressings and antibiotic coverage will also be advised for faster and better recovery.. Hope this information helps.. Thanks and regards. Dr.Honey Nandwani Arora.