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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Dosage Of Misoprostol During Pregnancy

Hi my doctor have advice me to take misoprostol 200 mcg as i m 7-8 weeks pregnant and this pregnancy will lead to miscarriage. I have done ultrasounds and blood works for 2-4 times and the result is that in ultrasound they cannot see baby and my hcg count is not getting double. So doctor have advice me to take misoprostol 200 mcg. I wanted to know how many tablets I can take at a time.
Tue, 5 Jan 2016
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General & Family Physician 's  Response
Hi & Welcome.
I can understand your concern.
Incomplete data like the route of administration of the Misoprostol tablets not mentioned.

The following guidelines to be followed for proper administration of Misoprostol to terminate the pregnancy up to 12 weeks.

Step 1: Insert 4 tablets of Misoprostol (200x4) deeply into the vagina OR in the mouth under the tongue or in the cheek pouch.
If the tablets are placed under the tongue or in the cheek pouch, hold in the mouth for 20-30 minutes to allow them to dissolve, and then swallow the remaining fragments.

Bleeding and uterine contractions (cramping) may begin half an hour following this first step and will almost always start within the first 12 hours. The majority of pregnancies up to 12 weeks duration are terminated within hours of the first administration of Misoprostol.
Bleeding itself does not mean that an abortion has occurred. Close inspection of the sanitary pad or other receptacle may reveal whether the pregnancy has been terminated.

If it is not clear that the pregnancy has been terminated (for example, if the embryonic sac is not visible on the sanitary pad or if cramping continues and has not begun to subside), go to Step 2.

Step 2: If tablets were administered vaginally in Step 1, insert 4 more tablets of Misoprostol deep into the vagina 3 to 12 hours after the first administration.

If tablets were administered by mouth in Step 1, place 4 more tablets under the tongue or in the cheek pouch 3 hours after the first administration and hold them there for 20-30 minutes until they dissolve.

Step 3: If the pregnancy has not been terminated after using the second set of pills and bleeding, insert 4 more tablets of Misoprostol 3 to 12 hours after the second vaginal administration or 3 hours after the second administration by mouth.

Hope the suggestions given above could be useful.
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Suggest Dosage Of Misoprostol During Pregnancy

Hi & Welcome. I can understand your concern. Incomplete data like the route of administration of the Misoprostol tablets not mentioned. The following guidelines to be followed for proper administration of Misoprostol to terminate the pregnancy up to 12 weeks. Step 1: Insert 4 tablets of Misoprostol (200x4) deeply into the vagina OR in the mouth under the tongue or in the cheek pouch. If the tablets are placed under the tongue or in the cheek pouch, hold in the mouth for 20-30 minutes to allow them to dissolve, and then swallow the remaining fragments. Bleeding and uterine contractions (cramping) may begin half an hour following this first step and will almost always start within the first 12 hours. The majority of pregnancies up to 12 weeks duration are terminated within hours of the first administration of Misoprostol. Bleeding itself does not mean that an abortion has occurred. Close inspection of the sanitary pad or other receptacle may reveal whether the pregnancy has been terminated. If it is not clear that the pregnancy has been terminated (for example, if the embryonic sac is not visible on the sanitary pad or if cramping continues and has not begun to subside), go to Step 2. Step 2: If tablets were administered vaginally in Step 1, insert 4 more tablets of Misoprostol deep into the vagina 3 to 12 hours after the first administration. If tablets were administered by mouth in Step 1, place 4 more tablets under the tongue or in the cheek pouch 3 hours after the first administration and hold them there for 20-30 minutes until they dissolve. Step 3: If the pregnancy has not been terminated after using the second set of pills and bleeding, insert 4 more tablets of Misoprostol 3 to 12 hours after the second vaginal administration or 3 hours after the second administration by mouth. Hope the suggestions given above could be useful.