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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suffering With Hypothyroidism, Difficulty In Conceiving Due Ti Implantation Problems. Help?

Hello. I am a 29 year female suffering from hypothyroidisim since the age of 13 years. Basically auto imune thyrodities with no family history. Have been on eltroxin 100 mcg recently the dose is 125 mcg. Recent reports show a low TSH with normal T3 T4 and very high anti thyroid antibodies . I am trying to conceive since last 2 years (married since 3 years) but all to its in-vain. Went for atleast 10 cycles of IUI but nothing is positive till date. Doctor says their is a problem in implantation which may be because of thyroid problems. Kindly help me with the solution to the problem.
Mon, 21 Jan 2013
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Infertility Specialist,  's  Response
Hi
Welcome to HealthcareMagic
Hypothyroidism usually causes Ovulatory disturbances and there is problem of egg growth or maturity. I am not very sure that it will also cause implantation failure. There are high incidence of patients with autoimmune thyroiditis to be associated with endometriosis which itself can cause infertility and implantation failure. There is no point in going ahead with IUI again. You need to undergo laparohysteroscopy to identify the underlying cause and to test patency of fallopian tubes. You can try 2 cycles of IUI immediately after surgery. If IUI fails then IVF ( Test tube baby ) is last resort. Continue taking thyroxin and regular follow up with thyroid profile is required.
Take care.
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Infertility Specialist,  Dr. Dattaprasad's  Response
Hi,
Thyroid problem, once corrected, is not the reason for infertility. Your case seems to fit into the definition of unexplained infertility. With 10 failed IUI cycles, its better to go for further step like IVF/ICSI for conception.
Wish you good health.
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Suffering With Hypothyroidism, Difficulty In Conceiving Due Ti Implantation Problems. Help?

Hi Welcome to HealthcareMagic Hypothyroidism usually causes Ovulatory disturbances and there is problem of egg growth or maturity. I am not very sure that it will also cause implantation failure. There are high incidence of patients with autoimmune thyroiditis to be associated with endometriosis which itself can cause infertility and implantation failure. There is no point in going ahead with IUI again. You need to undergo laparohysteroscopy to identify the underlying cause and to test patency of fallopian tubes. You can try 2 cycles of IUI immediately after surgery. If IUI fails then IVF ( Test tube baby ) is last resort. Continue taking thyroxin and regular follow up with thyroid profile is required. Take care.