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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suffering With CKD, Sarcoidosis, Have Reduced GFR Considerably. Taking Augmentin, Wysolone. Possible Reasons?

hi I m suffreign from CKD for 3 years now. My Creatine level is varies between 1.7 to 2.1 for last three years from may 2009. But my GFR is reducing to 39.1 ml/1.73cm3 from 49.1ml. In the meantime I have developed new problem for 1 year now which is Sarcoidisis, for that I have started wysolone 20 twice daily. Augmentin 1 gm twice daily. micinac 600 2 daily. I don t know why my GFR is deceresed although there is no major changein my cretinine level. Can you suggest me what are the possible ways
Sat, 17 Aug 2013
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Nephrologist,  's  Response
Hi
Thanks for the query.
GFR is calculated by a formula which uses serum creatinine as one of the parameters. The other parameters are age, sex, race, body weight.
Thus it is quite unusual for GFR to decrease if the serum creatinine is the same, unless you have lost some weight.
The reason for GFR decline can be natural progression of the disease or some new disease process. Your nephrologist is the best person to evaluate this.
Hope this helps
Good luck.
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Suffering With CKD, Sarcoidosis, Have Reduced GFR Considerably. Taking Augmentin, Wysolone. Possible Reasons?

Hi Thanks for the query. GFR is calculated by a formula which uses serum creatinine as one of the parameters. The other parameters are age, sex, race, body weight. Thus it is quite unusual for GFR to decrease if the serum creatinine is the same, unless you have lost some weight. The reason for GFR decline can be natural progression of the disease or some new disease process. Your nephrologist is the best person to evaluate this. Hope this helps Good luck.